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Clinical Studies
Acute infectious chorea in children: A study of 17 cases
1 Department of Neurology, Fann, Dakar, Senegal
2 Pediatric Neurology Department, Albert Royer Children’s Hospital, Dakar, Senegal
3 Albert Royer Children’s Hospital, Dakar, Senegal
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Khalifa Ababacar Mbaye
Neurologist and Neuropediatrician at the Fann Hospital in Dakar,
Senegal
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Article ID: 100017N06KM2022
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How to cite this article
Mbaye KA, Diagne R, Mbacké SS, Mbodji AB, Sow PS, Kane F, Ndiaye M. Acute infectious chorea in children: A study of 17 cases. Edorium J Neurol 2022;8:100017N06KM2022.ABSTRACT
Introduction: The objective of our study was to characterize the epidemiological, clinical, paraclinical, etiological, therapeutic, and evolutionary aspects of acute infectious chorea in children at the Albert Royer National Children’s Hospital.
Methods: This was a retrospective descriptive study from January 2005 to January 2020, which took place in the pediatric neurology unit of the Albert Royer National Children’s Hospital. All patients presenting with acute choreic syndrome in an infectious context and whose age was less than or equal to 16 years were included in our study. Patients with incomplete records were excluded.
Results: In 15 years, we collected 17 patients including 9 girls. The average age was 8.41 years. Clinically, chorea was generalized in 14 patients (82.35%) and localized in 3 patients (17.64%). Brain magnetic resonance imaging (MRI) showed panencephalitis in two patients and bithalamic and cortical hypersignals in one patient. Twelve patients were diagnosed with Sydenham’s chorea (SC) (70.58%), four patients had chorea following herpes simplex infection and one patient had chorea secondary to enterovirus. Haloperidol was the most used treatment. The evolution was favorable for all children diagnosed with SC compared to other causes of chorea (viral chorea).
Conclusion: Chorea is a rare pathology in children and is dominated in our context by SC.
Keywords: Children, Chorea, Infectious, Senegal
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Author Contributions
Khalifa Ababacar Mbaye - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Rokhaya Diagne - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Serigne Saliou Mbacké - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ahmadou Bamba Mbodji - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published
Papa Souleye Sow - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Fatou Kane - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published
Moustapha Ndiaye - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Khalifa Ababacar Mbaye et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
